Chemical investigations have detected seven groups of medicinally active compounds in H. Perforatum . They include naphthodianthrones, phloroglucinols, and flavonoids (such as phenylpropanes, flavonol glycosides, and biflavones), as well as essential oils . There two major active constituents have been identified: hypericin (a naphtodianthrone) and hyperforin (a phloroglucinol).
The class of compounds isolated from H. perforatum and the one which is the most researched naphthodianthrones . They include hypericin, pseudohypericin, isophypericin, and protohypericin . Of these, hypericin—an anthraquinone derived pigment that is responsible for the red color of SJW oils. Hypericin is found in the flowers in the form of black dots that are located along the petals. Due to its chemical structure, hypericin is highly photoreactive.
Flavonoids in HP range from 7% in stems to 12% in flowers and leaves . Flavonoids include flavonols (kaempferol, quercetin), flavones (luteolin), glycosides (hyperside, isoquercitrin, and rutin), biflavones (biapigenin), amentoflavone, myricetin, hyperin, oligomeric proanthocyanadins, and miquelianin, all of which are biogenetically related 2, 47.
Extracts of HP contain several classes of lipophilic compounds with demonstrated therapeutic value, including phloroglucinol derivatives and oils. Hyperforin, isolated in concentrations of 24.5% , is a prenylated phloroglucinol. Hyperforin is unstable in the presence of both light and oxygen . Other phloroglucinols include adhyperforin (0.2%1.9%), furohyperforin, and other hyperforin analogs . Essential oils are found in concentrations ranging from 0.05% to 0.9% . They consist mainly of mono and sesquiterpenes, specifically 2- methyloctane, nonane, α and β pinene, α terpineol, geranil, and trace amounts of myrecene, limonene, and caryophyllene .
These include tannins (ranging from 3% to 16%), xanthones (1.28 mg/100g), phenolic compounds (caffeic acid, chlorogenic acid, and pcoumaric acid), and hyperfolin. Additional compounds include acids (nicotinic, myristic, palmitic, and stearic), carotenoids, choline, pectin, hydrocarbons, and long chain alcohols .
Common names: perforate St John’s-wort, St. John’s wort oil, Hypericum perforatum.
This is a home made completely natural good using the best ingredients in terms of quality with respect to natural environment .For this reason the produced quantity will not exceed 10000 ml annually
Medical Reports On Hypericum Perforatum Oil :
History and therapeutic properties of Hypericum Perforatum from antiquity until today.
Medical Attributes of St. John’s Wort (Hypericum perforatum)
Hypericin–the facts about a controversial agent.
Effect of St.John’s wort (Hypericum perforatum) oily extract for the care and treatment of pressure sores; a case report.
THERAPEUTIC POTENTIAL OF HYPERICUM PERFORATUM: A REVIEW